Researchers at Indiana University and international collaborators have published results showing that a molecule combining the properties of two endocrine hormones is an effective treatment for adult-onset diabetes. The research ...
Oct 30, 2013
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Researchers at The University of Texas MD Anderson Cancer Center have discovered a novel function for the metabolic enzyme medium-chain acyl-CoA dehydrogenase (MCAD) in glioblastoma (GBM). MCAD prevents toxic lipid buildup, ...
May 26, 2021
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It usually takes 10 to 15 years to develop a new drug, and they cost around US$2.6 billion each. Because it's difficult to predict how a drug candidate will interact with human cells, many drugs never pass clinical trials. ...
Jul 27, 2021
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Scientists have shown that two existing drug candidates—JAK inhibitors and Mepron—hold potential as treatments for a deadly acute myeloid leukemia (AML) subtype that is more common in children.
Apr 14, 2021
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Sleeping sickness kills tens of thousands of people in Africa each year. Current chemotherapies are subject to various limitations, including resistance. Rhodesain, an enzyme of the parasites that cause this illness (human ...
May 17, 2013
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In 2020, the Sean M. Healey & AMG Center at Massachusetts General Hospital launched the first platform trial for amyotrophic lateral sclerosis (ALS), in which multiple treatments are tested and evaluated simultaneously to ...
Jan 8, 2021
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A new study conducted by scientists from the Dana-Farber Cancer Institute at Harvard Medical School and Karolinska Institutet in Sweden presents very promising results for the treatment of the cancer form multiple myeloma. ...
Dec 6, 2013
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New research conducted by scientists at the University of Sheffield into a drug candidate which could help to delay the onset of motor neurone disease has shown encouraging early results.
May 25, 2017
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A newly developed assay may help investigators identify novel drug candidates to protect kidney cells and prevent or treat chronic kidney disease (CKD). The advance is described in an upcoming issue of the Journal of the ...
Apr 9, 2015
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Researchers from Rutgers believe themselves among the leaders in a race to find an oral COVID-19 treatment to supplement or replace Paxlovid—the antiviral medication that helps keep high-risk patients out of the hospital ...
Jan 9, 2024
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