Genetics
How genetics influence immunity in patients with type 1 diabetes
New insights into how genetic factors affect the body's immune response in type 1 diabetes have been published in eLife.
Jun 7, 2022
0
18
News tagged with drug candidate
Diseases, Conditions, Syndromes
Preclinical data for COVID-19 vaccine candidate show effectiveness and advantages
A COVID-19 vaccine candidate that underwent extensive preclinical testing at the University of Alabama at Birmingham this spring and summer shows potent preclinical immune responses—including several that distinguish it ...
Oct 13, 2020
0
5
Immunology
Antibody therapeutic candidate reduces immune complexes involved in autoimmune diseases
A broad variety of autoimmune diseases involve the development of pathogenic immunoglobulin G (IgG) antibodies which can attack cells and tissues and form immune complexes with the antigen to which they are directed. Immune ...
Dec 18, 2019
0
50
Medical research
Reinvigorating the clinical drug pipeline for TB
A research team led by scientists from the Broad Institute has uncovered a novel group of chemical inhibitors that can kill the bacteria that causes tuberculosis (TB). Importantly, these chemical compounds take aim at a previously ...
Jun 20, 2019
0
0
Medications
Computer program narrows drug candidates for treating COVID-19
While vaccination and public education concerning the transmission of the coronavirus causing COVID-19 have been at the forefront of our response to the pandemic, there remains an urgent need for pharmaceutical interventions ...
Mar 24, 2022
0
2
Oncology & Cancer
Cancer biology: Targeting tumors with 'stapled' peptides
(Phys.org) —Designer peptides containing chemically stabilized helices emerge as a potent way to activate anti-tumor proteins inside cells.
Jul 17, 2013
0
0
Medical research
How to pick a winner in clinical drug trials
When a drug fails late on in clinical trials it's a major setback for launching new medicines. It can cost millions, even billions, of research and development funds. Now, an 'adaptive' approach to clinical trials and a genetic ...
Jun 27, 2017
0
4
Immunology
Genome study identifies three possible drug candidates for autoimmune diseases
(Medical Xpress)—New pharmaceuticals to fight autoimmune diseases, such as multiple sclerosis, rheumatoid arthritis and psoriasis, may be identified more effectively by adding genome analysis to standard drug screening, ...
May 2, 2014
0
0
Medications
Sea anemone venom-derived compound effective in anti-obesity studies
Scientists at UC Irvine reported this week that a synthetic compound ShK-186, originally derived from a sea anemone toxin, has been found to enhance metabolic activity and shows potential as a treatment for obesity and insulin ...
May 27, 2013
1
0
Oncology & Cancer
First made-in-Singapore cancer drug enters clinical testing
A made-in-Singapore cancer drug has advanced into clinical trials, charting a milestone in Singapore's biomedical sciences initiative that will go towards improving the lives of cancer patients in Singapore, and worldwide. ...
Jul 16, 2015
0
23
