Researchers have created a new open-access database of information on drug candidates and how they are metabolized by the body, which could help speed up the repurposing of old drugs as new treatments.
Aug 3, 2021
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It usually takes 10 to 15 years to develop a new drug, and they cost around US$2.6 billion each. Because it's difficult to predict how a drug candidate will interact with human cells, many drugs never pass clinical trials. ...
Jul 27, 2021
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Researchers at The University of Texas MD Anderson Cancer Center have discovered a novel function for the metabolic enzyme medium-chain acyl-CoA dehydrogenase (MCAD) in glioblastoma (GBM). MCAD prevents toxic lipid buildup, ...
May 26, 2021
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Patients who have surgery for esophageal cancer commonly see the disease return, but a drug that boosts the immune system may help delay or prevent that, a new trial has found.
Apr 1, 2021
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Scientists at Sanford Burnham Prebys Medical Discovery Institute have identified a drug candidate that blocks the uptake of glutamine, a key food source for many tumors, and slows the growth of melanoma. The drug is a small ...
Mar 19, 2021
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Scientists at Sanford Burnham Prebys Medical Discovery Institute demonstrated for the first time that blocking 'cell drinking,' or macropinocytosis, in the thick tissue surrounding a pancreatic tumor slowed tumor growth—providing ...
Mar 17, 2021
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In 2020, the Sean M. Healey & AMG Center at Massachusetts General Hospital launched the first platform trial for amyotrophic lateral sclerosis (ALS), in which multiple treatments are tested and evaluated simultaneously to ...
Jan 8, 2021
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Researchers at the University of Tennessee Health Science Center working with colleagues at the University of New Mexico have identified three drugs, already approved for other uses in humans, as possible therapeutics for ...
Nov 18, 2020
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A second experimental COVID-19 vaccine—this one from Moderna Inc.—yielded extraordinarily strong early results Monday, another badly needed dose of hope as the pandemic enters a terrible new phase.
Nov 16, 2020
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The United States on Tuesday registered a record 200,000 new COVID-19 cases in one day, highlighting the desperate need for a vaccine after results from one medical trial fuelled optimism around the world.
Nov 10, 2020
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