Medical research

Researchers develop 'dimmer switch' to help control gene therapy

In a major advancement in the field of gene therapy for rare and devastating diseases, researchers at Children's Hospital of Philadelphia (CHOP) have developed a "dimmer switch" system that can control levels of proteins ...

Oncology & Cancer

Nanotech'ed RNA drug reduces ovarian cancer tumors by 83 percent

By loading fragile RNA into silicon nanoparticles, researchers from The Methodist Hospital and two other institutions found a new drug delivery system can reduce the size of ovarian tumors by as much as 83 percent—and stop ...

Ophthalmology

Contact lens-based antihistamine delivery effective

(HealthDay)—A contact lens (CL)-based drug delivery system is effective for therapeutic delivery of the antihistamine ketotifen, according to a study published online March 19 in Cornea.

Arthritis & Rheumatism

Light helps arthritis treatments target joints

Although today's rheumatoid arthritis treatments can reduce symptoms, they often come with serious side effects. Results from a new mouse study suggest that a new light-activated drug delivery method helps confine treatments ...

Medical research

Breaking through the blood-brain barrier

To mark the European Month of the Brain, we look at one EU-funded project that has focussed efforts on drug delivery across the so-called blood-brain barrier. The blood-brain barrier (BBB), while preforming a key protective ...

Genetics

Treating cystic fibrosis with mRNA therapy or CRISPR

The potential for treating cystic fibrosis (CF) using mRNA therapies or CRISPR gene editing is possible regardless of the causative mutation. CF clinical trials showing that a genotype-agnostic gene therapy for CF is possible ...

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