The Ivy Brain Tumor Center at the Barrow Neurological Institute, has released the results of its recent Phase 0 clinical trial of the breast cancer drug ribociclib (Kisqali) for the treatment of recurrent glioblastoma. The ...
Jul 25, 2019
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Children born to women on HIV therapy containing the drug dolutegravir since conception have a slightly higher risk of neural tube defects, compared to children born to women on regimens of other antiretroviral drugs. The ...
Jul 22, 2019
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A bone cancer known as osteosarcoma is genetically similar in dogs and human children, according to the results of a study published today by Tufts University and the Translational Genomics Research Institute (TGen), an affiliate ...
Jul 19, 2019
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(HealthDay)—A staging system of β-amyloid (Aβ) accumulation may be useful for monitoring patients throughout the course of Alzheimer disease (AD), according to a study published online July 17 in JAMA Neurology to coincide ...
Jul 18, 2019
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In spite of increasing demand, the number of newly developed drugs decreased continuously in the past decades. The search for new active substances, their production, characterization, and screening for biological effectiveness ...
Jul 15, 2019
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Cleveland Clinic's fourth annual analysis of Alzheimer's disease drug development found that the pipeline has grown in the number and variety of agents being tested over the past year, while highlighting several advances ...
Jul 10, 2019
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A reconfigurable "body-on-a-chip" model could transform drug development by simultaneously measuring compound efficacy and toxicity, for both target cells and other organs, such as the heart and liver. These findings, published ...
Jun 19, 2019
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Testing new pharmaceutical treatments is a complicated process. Very often, participants have preferences or hopes, either about what the test should measure or about what the outcome should be. Patients often enrol in the ...
Jun 18, 2019
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(HealthDay)—Vinpocetine, a compound found in many dietary supplements, may pose a risk to women of childbearing age, U.S. health officials warn.
Jun 4, 2019
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Morphine and other opioid-based painkillers are very effective at treating pain initially, but studies have shown that the drugs can make patients more pain-sensitive, prolonging their discomfort and increasing their risks ...
May 21, 2019
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