Gerontology & Geriatrics
Artificial intelligence for aging research in cancer drug development
A new editorial paper was published in Aging, entitled, "Artificial intelligence for aging research in cancer drug development."
Dec 7, 2023
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News tagged with drug development
Immunology
Researchers discover metabolic pathway specific to granuloma formation in patients
On good days, the immune system can effectively handle pathogens that invade the body. However, when foreign matter takes the upper hand, the body builds a wall of immune cells called granuloma around the pathogens to isolate ...
Dec 7, 2023
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Medical research
Selective CDK2 inhibitor drug can stop cancer growth, animal study suggests
A new Peter Mac study using a pioneering drug has successfully controlled the growth of tumors and overcome existing drug resistance in multiple cancer types.
Dec 7, 2023
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Genetics
Accelerating drug development for lung diseases: New insights from single-cell genomics
Drug development for lung diseases is complicated. Most clinical trials that test novel drugs fail due to the fact that laboratory models cannot accurately replicate human physiology.
Dec 6, 2023
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Medical research
This gross mixture has big benefits for the study of bacteria
Animal models are a necessary research tool for understanding how diseases develop and how therapies work in biological systems and can be credited for breakthroughs ranging from effective antibiotics to the COVID-19 vaccines.
Nov 30, 2023
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Oncology & Cancer
Applications of macrocyclic molecules in cancer therapy: Target cancer development or overcome drug resistance
A study, by Professor Xiaoling Song, Professor Biao Jiang and Pr. Xiaoling Song and Ph.D. student, Yifan Wu (Shanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University), on the application of macrocyclic ...
Nov 30, 2023
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Cardiology
First multi-chamber heart organoids unravel human heart development and disease
Heart disease kills 18 million people each year, but the development of new therapies faces a bottleneck: no physiological model of the entire human heart exists—so far. A new multi-chamber organoid that mirrors the heart's ...
Nov 28, 2023
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Diseases, Conditions, Syndromes
Vaccine to prevent a dangerous tropical disease receives approval
The chikungunya virus is widespread in tropical regions, where it is spread to humans by mosquitoes of the genus Aedes. Chikungunya is characterized by high fever, headache, muscle and joint pain, rash, and sometimes diarrhea. ...
Nov 22, 2023
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Genetics
Newly identified SARS-CoV-2 infection pathway provides clues to severe COVID-19 cases and obesity link
Researchers at Cleveland Clinic have identified a new way that the SARS-CoV-2 virus hijacks its host's translation machinery using elements within its genetic material and causes COVID-19, paving the way for future study.
Nov 14, 2023
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Immunology
Reviewing new challenges and opportunities for hepatitis B cures
Hepatitis B virus (HBV) is a significant public health problem, with over 296 million people chronically infected worldwide. Despite the availability of a safe and effective vaccine for over 40 years, HBV remains a leading ...
Nov 13, 2023
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