Oncology & Cancer

Critical oncology trial data remains hidden

Despite a commitment from the pharmaceutical industry in 2014 to improve data transparency, more than half of the clinical trials that led to the United States Food and Drug Administration approving anticancer medicines over ...

Diseases, Conditions, Syndromes

A roadmap for the future of hepatitis B therapy development

Worldwide, 880,000 people die each year as a result of infection with the hepatitis B virus (HBV). Antiviral drugs that can suppress replication of the virus are available. However, these must be taken for decades, as there ...

Addiction

Oklahoma reaches opioid settlement with 3 drug companies

Oklahoma officials have reached an opioid settlement with three drug companies that would bring more than $250 million to finance efforts to battle opioid addiction, state Attorney General John O'Connor has announced.

Health

US seeks to drastically cut nicotine content in cigarettes

President Joe Biden's administration on Tuesday announced it would develop a new policy requiring cigarette producers to reduce nicotine to non-addictive levels—a move that would deal a powerful blow to the tobacco industry.

Neuroscience

Repurposing cancer drug to treat neuroinflammation

The repurposing of FDA-approved drugs for alternative diseases is a faster way of bringing new treatments into the clinic. Researchers at Karolinska Institutet in Sweden have repurposed a cancer drug for treatment of neuroinflammatory ...

Oncology & Cancer

New computer simulation cracks mystery of cancer drug resistance

Imatinib, better known as Gleevec, was hailed as a "miracle" cancer drug when it entered the market in the early 2000s. Though it has been highly successful at treating early-stage chronic myeloid leukemia (CML)—a rare ...

Gastroenterology

Mixing drugs into oil-based gels could help the medicine go down

For most children and even some adults, swallowing pills or tablets is difficult. To make it easier to give those medicines, researchers at MIT and Brigham and Women's Hospital have created a drug-delivering gel that is much ...

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