Site 1 sodium channel blockers such as tetrodotoxin and saxitoxin are small-molecule drugs with powerful local anesthetic properties. They provide pain relief without toxic effects on local nerves and muscles, and are an ...
Sep 13, 2021
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Much progress has been made on the development of vaccines aiming at triggering human immunity to SARS-CoV-2, the virus that causes COVID-19. In addition, researchers at Baylor College of Medicine are involved in the development ...
Aug 31, 2021
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Until recently, babies and children with spinal muscular atrophy (SMA) lacked any type of treatment capable of stopping the neuromuscular disease from progressing. In SMA, damaged motor neurons in the spinal cord fail to ...
Aug 20, 2021
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A new combination of drugs that may have the potential to treat a type of leukemia has been uncovered by a detailed molecular examination of leukemia cells by RIKEN researchers1.
Jun 28, 2021
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Structural biologists at St. Jude Children's Research Hospital have determined the detailed structure of an enzyme whose mutated forms are known to cause Parkinson's disease. The achievement opens a research pathway to develop ...
Jun 9, 2021
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The drug diABZI—which activates the body's innate immune response—was highly effective in preventing severe COVID-19 in mice that were infected with SARS-CoV-2, according to scientists in the Perelman School of Medicine ...
May 28, 2021
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Scientists have for the first time revealed the structure surrounding important receptors in the brain's hippocampus, the seat of memory and learning.
May 12, 2021
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A discovery involving multiple teams from across Scripps Research has revealed a powerful new approach for treating diabetic foot ulcers, which affect millions of people in the US and often lead to serious complications.
Mar 23, 2021
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In recent years, therapeutic antibodies have transformed the treatment of cancer and autoimmune diseases. Now, researchers at Lund University in Sweden have developed a new, efficient method based on the 'genetic scissors' ...
Mar 5, 2021
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For scientists hoping to harness a powerful new technique for demolishing cellular enzymes known as kinases, the choices can be a bit overwhelming. Some 514 different protein kinases toil in human cells, representing 2.5% ...
Dec 3, 2020
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