Psychology & Psychiatry

Nucleus accumbens recruited by cocaine, sugar are different

Nucleus accumbens in the brain play a central role in the risk-reward circuit. Their operation is based chiefly on three essential neurotransmitters: dopamine, which promotes desire; serotonin, whose effects include satiety ...

Psychology & Psychiatry

Suicide deaths among youth following antidepressant boxed warnings

A public health advisory issued by the US Food and Drug Administration (FDA) in 2003, followed by drug label warnings, indicated that children and adolescents taking antidepressants were at increased risk of developing suicidal ...

Oncology & Cancer

Scientists kill cancer cells by 'shutting the door' to the nucleus

Scientists at Sanford Burnham Prebys Medical Discovery Institute have shown that blocking the construction of nuclear pores complexes—large channels that control the flow of materials in and out of the cell nucleus—shrank ...

Oncology & Cancer

Halting cancer by halting DNA repair

PARP inhibitors are rapidly transforming the treatment of ovarian, breast, prostate and other types of cancer. To develop these drugs, researchers supported by Cancer Research UK had to decipher how blocking DNA repair could ...

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