As the first clinical trial of the drug novobiocin is about to open for patients with cancers carrying BRCA gene mutations, new research at Dana-Farber Cancer Institute shows the drug poses a double threat to tumor cells.
Mar 14, 2023
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Barely a month goes by without headlines announcing yet another advancement in cancer vaccines.
Mar 7, 2023
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On the road, putting a foot on the gas or brake pedal controls the car's speed. This also happens in our body, in driving an immune response. Like human drivers, antibodies have a "foot"—a sort of molecular limb that "presses" ...
Mar 6, 2023
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Cancer cells have an innate randomness in their ability to respond to chemotherapy, which is another tool in their arsenal of resisting treatment, new research led by the Garvan Institute of Medical Research shows.
Mar 3, 2023
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A new study led by researchers at Harvard Medical School details the step-by-step cascade that allows bacteria to break through the brain's protective layers—the meninges—and cause brain infection, or meningitis, a highly ...
Mar 1, 2023
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Immune cells that keep the brain free of debris but also contribute to inflammation are the likely culprits behind the concentration and memory problems that sometimes follow one type of chemotherapy, a new study in mice ...
Feb 28, 2023
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Researchers from the Organoid group (former Clevers group, Hubrecht Institute) together with researchers from the Princess Máxima Center for pediatric oncology have established novel human organoid models of fatty liver ...
Feb 23, 2023
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Scientists have identified the brain structures responsible for compulsive drug-seeking behaviors due to repeated use of cocaine. The findings, published in Biomedicines, identifies the structures involved and neural pathways ...
Feb 10, 2023
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Patients with glioblastoma—the deadliest type of primary brain tumor—may potentially benefit from immunotherapy medications called immune checkpoint inhibitors that stimulate an immune response against cancer cells.
Feb 2, 2023
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Immunity from COVID-19 appears to gather strength with more time between vaccination and infection, a new laboratory study from researchers at Oregon Health & Science University suggests. The findings carry implications for ...
Jan 25, 2023
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