Cell lines form the backbone of cancer research. These individual groups of cells, typically collected from patients' tumor samples and cultured to grow indefinitely in the laboratory, enable everything from basic genetic ...
Aug 9, 2018
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Using a combination of genetic engineering and laser technology, researchers at the University of North Carolina at Chapel Hill have manipulated brain wiring responsible for reward-seeking behaviors, such as drug addiction. ...
Jun 29, 2011
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University of Oklahoma researchers have deepened their understanding of a drug's ability to prevent fat buildup in the liver, a condition that often occurs with obesity and can lead to serious fatty liver disease. Their findings—which ...
May 23, 2024
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Stanford Medicine researchers have discovered a possible new way to treat pain without the use of opioids. By targeting a specific area of a well-known pain receptor, they were able to reduce pain sensitivity in mice without ...
Feb 2, 2023
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Cells in the surrounding tumor microenvironment have a significant impact on cancer growth, survival and responses to therapy. Cancer-associated fibroblasts in the tumor environment have typically been associated with tumor ...
Aug 16, 2022
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Parkinson's is a progressive and debilitating disease of the brain that eventually compromises patients' ability to walk and even to talk. Its diagnosis is complex, and in the early stages—impossible.
Jul 15, 2022
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Most cancer treatments are based on using the maximum tolerated dose of a drug to kill as many cancer cells as possible. While this approach has led to patients achieving good responses to therapy, most patients develop drug ...
May 9, 2022
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Researchers from Indiana University School of Medicine are discovering new ways to find out how effective a drug might be against cancer. Their findings are detailed in a new paper published by Science Advances.
Jan 17, 2022
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Through large-scale profiling of protein changes in response to drug treatments in cancer cell lines, researchers at The University of Texas MD Anderson Cancer Center have generated a valuable resource to aid in predicting ...
Nov 5, 2020
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The primary method used to test compounds for anti-cancer activity in cells is flawed, Vanderbilt University researchers report May 2 in Nature Methods. The findings cast doubt on methods used by the entire scientific enterprise ...
May 2, 2016
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