Medications
Scientists shed light on action of key tuberculosis drug
A new study led by scientists at the University of Birmingham has shed fresh light on how a key front-line drug kills the tuberculosis bacterium.
Apr 23, 2020
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Page 12 - News tagged with drug targets
Medical research
Scientists enhance new way to overcome resistance to targeted cancer treatments
Researchers have enhanced a new method for inhibiting the protein HSP72, known to be important in helping cancer cells survive and resist treatment, which will help scientists move closer to discovering a new cancer drug ...
Apr 6, 2020
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Oncology & Cancer
Drug that keeps surface receptors on cancer cells makes them more visible to immune cells
A drug that is already clinically available for the treatment of nausea and psychosis, called prochlorperazine (PCZ), inhibits the internalization of receptors on the surface of tumor cells, thereby increasing the ability ...
Mar 5, 2020
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Neuroscience
Genetic screen offers new drug targets for Huntington's disease
Using a type of genetic screen that had previously been impossible in the mammalian brain, MIT neuroscientists have identified hundreds of genes that are necessary for neuron survival. They also used the same approach to ...
Jan 30, 2020
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Medical research
Coronavirus therapies slowed by intermittent nature of outbreaks
As the Wuhan coronavirus outbreak causes worldwide concern, Purdue University scientists say control measures are an absolute necessity and that medical treatments for similar disease are on the horizon.
Jan 23, 2020
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Genetics
Large study of genetic differences reveals several new targets for variety of diseases
While subtle differences in the number of genes copied from one individual and passed down to the next can be found in many healthy people, their role in disease may be much greater than previously thought.
Jan 14, 2020
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Alzheimer's disease & dementia
Alzheimer's study shows promise in protecting brain from tau
In the wake of recent disappointments over clinical trials targeting amyloid plaque build-up in Alzheimer's disease, researchers are focusing more attention on misfolded tau protein, another culprit in brain diseases that ...
Dec 18, 2019
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Diseases, Conditions, Syndromes
Emerging role of adenosine in brain disorders and amyotrophic lateral sclerosis
The role of adenosine in neurodegeneration and neuroregeneration has led to growing attention on adenosine receptors as potential drug targets in a range of brain disorders, including neuroregenerative therapy and treatment ...
Dec 7, 2019
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Oncology & Cancer
More efficient drug delivery within the brain by utilizing LAT1
According to a new study carried out at the University of Eastern Finland, the distribution of drug molecules within the brain can be improved by utilizing LAT1, which is expressed highly in the brain. By converting drug ...
Sep 24, 2019
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Genetics
Scientists hone in on DNA differences behind immune diseases
Scientists are one step closer to discovering the causes of immune diseases such as asthma, multiple sclerosis and arthritis. Research from the Wellcome Sanger Institute, GSK and Biogen, under the Open Targets initiative, ...
Sep 23, 2019
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