Medical research

Targeted therapy for 'undruggable' lung cancer

Over the past two decades, targeted cancer therapies have changed the prognosis for thousands of patients. By targeting the specific genetic mutation behind a patient's cancer, these therapies have enabled increasing numbers ...

Oncology & Cancer

Predicting resistance to anticancer drugs

Cancer cells can develop resistance to therapy through both genetic and non-genetic mechanisms. But it is unclear how and why one of these routes to resistance prevails. Understanding this 'choice' by the cancer cells may ...

Medical research

DOE scientists deploy creativity, speed to disrupt COVID-19

In early 2020, when the novel coronavirus was gaining momentum but had not yet been named a pandemic, computational chemist Marti Head of Oak Ridge National Laboratory—along with scientists and researchers around the globe—abruptly ...

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