The effects of KRAS mutations underlying many different types of cancer are more diverse than previously thought, according to a new study led by the University of Eastern Finland. Different mutations in the same amino acid ...
Sep 11, 2018
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A University of North Carolina Lineberger Comprehensive Cancer Center study may provide insights into how to overcome barriers to using immune-based treatments for pancreatic cancer, the third most deadly cancer in the United ...
Aug 6, 2018
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Patient-derived organoids, hollow spheres of cells cultured from tumors, can quickly and accurately predict how patients with pancreatic cancer respond to a variety of treatments, facilitating a precision-medicine approach ...
May 31, 2018
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The population of bacteria in the pancreas increases more than a thousand fold in patients with pancreatic cancer, and becomes dominated by species that prevent the immune system from attacking tumor cells.
Mar 22, 2018
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Bacterial load was significantly higher in pancreatic tumor samples from patients with pancreatic ductal adenocarcinoma compared with pancreatic tissue from normal individuals, and in studies using mice, eliminating certain ...
Mar 22, 2018
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Genentech researchers have identified an enzyme that shifts pancreatic cancer cells to a more aggressive, drug-resistant state by epigenetically modifying the cells' chromatin. The study, which will be published December ...
Dec 11, 2017
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Pancreatic cancer is one of the most aggressive forms of cancer and is currently very difficult to treat. However, the last few years have seen advances in the scientific understanding of how this cancer develops at a molecular ...
Dec 5, 2017
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A new study of patients who underwent curative surgical removal of a pancreatic ductal adenocarcinoma showed that two of the nine preoperative factors analyzed were strongly predictive of poor prognosis regardless of the ...
Aug 10, 2017
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(HealthDay)—Curcumin can resensitize chemoresistant pancreatic ductal adenocarcinoma (PDAC) cells through inhibition of the polycomb repressive complex 2 (PRC2)-PVT1-c-Myc axis, according to a study published online July ...
Aug 2, 2017
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Cells, just like people, have memories. They retain molecular markers that at the beginning of their existence helped guide their development. Cells that become cancerous may be making use of these early memories to power ...
Jul 27, 2017
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