Diseases, Conditions, Syndromes

Sex differences in kidney injury

Evidence indicates men have higher incidence of chronic kidney disease and quicker renal decline than premenopausal women. However, sex differences in the expression and activation of the EGF receptor (EGFR), which mediates ...

Diseases, Conditions, Syndromes

Higher eGFR at dialysis initiation tied to lower survival in children

(HealthDay)—In children with end-stage renal disease (ESRD), a higher estimated glomerular filtration rate (eGFR) at dialysis initiation is associated with lower survival, particularly among children whose initial treatment ...

Medical research

Peripherally inserted central catheters often used in CKD

(HealthDay)—Peripherally inserted central catheters (PICCs) are frequently used in hospitalized patients with stage 3b or greater chronic kidney disease (estimated glomerular filtration rate [eGFR],

Oncology & Cancer

At molecular level, cancer mutations echo Darwin's observations

There are more than 100 mutations of the protein behind the deadly brain cancer, glioblastoma, however an international research team has discovered something these mutations have in common. The new understanding could lead ...

Oncology & Cancer

Semaphorin linked to lung cancer treatment resistance

Lung cancer remains a major cause of mortality across the globe, although we are gaining a deeper understanding of the genetic background behind this disease, including the mutations that promote it. Mutation in the gene ...

Oncology & Cancer

Cancer researchers identify 'Achilles heel' of drug-resistant tumors

UC San Francisco scientists have figured out why some lung cancers become drug-resistant after initially responding to targeted therapies. In the process, they devised a new two-pronged approach that yields an effective treatment ...

Oncology & Cancer

Will tarloxotinib finally break the HER2 barrier in lung cancer?

The HER2 gene is a well-known driver of breast cancer, where changes in this gene are found in about 1-in-5 cases of the disease. HER2 also contributes to about 3 percent of lung cancers, representing about 6,500 patients ...

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EGFR

EGFR is a four letter abbreviation that may refer to:

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