Obstetrics & gynaecology

Extending women's fertility and reversing aging in human egg cells

Throughout much of the world, increasing numbers of women are delaying having their first child until they are in their late thirties, and even into their forties. At this age, their eggs are rapidly deteriorating and, even ...

Genetics

How stress in the intestine influences chromosome inheritance

Inheriting a normal and intact number of chromosomes in germ cells, egg and sperm, is essential for the preservation of all species. With increasing age, the risk of the egg cell not inheriting the normal set of chromosomes ...

Oncology & Cancer

Glioblastoma dependent on biotin distribution

Glioblastoma is the most lethal and malignant adult brain cancer that may arise from neuroglial stem or progenitor cells. Certain gene mutations or those with a known history of other cancers and radiation therapy may predispose ...

Medical research

Building the ovarian environment from stem cells

Researchers led by Kyushu University have succeeded in using mouse stem cells to reconstruct structures in the ovarian environment critical for the generation of mature egg cells. Moreover, they were able to apply their findings ...

Gerontology & Geriatrics

How age affects male fertility

In 2012, proud dad Ramjit Raghav made global headlines when he became a father at the age of 96. He had beaten the record for the world's oldest dad—a record he'd set himself, two years earlier, at the age of 94.

Medical research

Single-cell technique could provide 'egg health' indicators

Using the power of single-cell analysis, researchers at the Babraham Institute have assessed the effects of age on egg cells (oocytes) in mice, particularly looking to identify genomic and epigenetic factors that relate to ...

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