Oncology & Cancer

Study shows new strategy to boost immune system to fight melanoma

A new study led by Yale Cancer Center researchers shows that the enzyme KDM5B suppresses anti-melanoma immunity. These findings could help develop a new treatment strategy to benefit patients with melanoma and other cancers, ...

Neuroscience

Mapping the mouse brain, and by extension, the human brain too

The circuits of the human brain contain more than 100 billion neurons, each linked to many other neurons via thousands of synaptic connections, resulting in a three-pound organ that is profoundly more complex than the sum ...

Medical research

Overcoming obstacles to promote repair in multiple sclerosis

In the nearly 1 million Americans living with multiple sclerosis, the fatty substance that insulates the nerves of the central nervous system—called myelin—is damaged. This slows the transmission of signals from their ...

Genetics

Beware the 'molecular parasites' involved in aging and disease

If you've ever seen a petunia with artfully variegated petals, then you've seen transposons at work. The flower's showy color patterns are due to transposable elements, or DNA sequences that can move locations within a genome. ...

Diabetes

Examining the genomics of pregnancy-induced diabetes

Pregnancy-induced diabetes, also known as gestational diabetes, is a common metabolic complication of pregnancy. The disorder carries a significant risk of adverse obstetric outcome. Additionally, it is associated with a ...

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