Diseases, Conditions, Syndromes

Unique mechanism of action inhibiting paracellular phosphate absorption

Ardelyx, Inc. today announced that the novel mechanism of action for tenapanor for the treatment of hyperphosphatemia, or elevated serum phosphorus, has been published in the peer-reviewed journal Science Translational Medicine. ...

Surgery

Pig hearts may save human lives: researchers

One day, cardiac patients may enjoy a new lease on life with pig hearts beating in their chests, said researchers reporting a major advance Tuesday in cross-species organ transplantation.

Genetics

Hybrid protein deregulates complement in dense deposit disease

Dense deposit disease is a rare congenital disorder that is associated with complement dysfunction and often results in end stage renal disease within 10 years of the initial diagnosis. A small percentage of dense deposit ...

Medical research

Scientists offers way to disrupt fibrosis

A team of scientists that includes Saint Louis University researchers has identified a new way to intervene in the molecular and cellular cascade that causes fibrosis – a condition where the body's natural process of forming ...

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