Medical research

A 12-hour biological clock coordinates essential bodily functions

Some bodily activities, sleeping, for instance, mostly occur once every 24 hours; they follow a circadian rhythm. Other bodily functions, such as body temperature, cognitive performance and blood pressure, present an additional ...

Diabetes

Molecular aid to insulin secretion identified

Blood sugar triggers the secretion of insulin from cells in the pancreas, a process that is impaired in diabetes. A team of Yale researchers have identified a mechanism at the membranes of these pancreatic cells that controls ...

Medical research

Peroxisomes—the hybrid organelle

Like the human body itself, cells have structures within them that perform special tasks. These cellular structures are called organelles, and discovering more about organelles is key to unlocking the reasons why certain ...

Neuroscience

Scientists develop new drug screening tool for dystonia

Duke University researchers have identified a common mechanism underlying separate forms of dystonia, a family of brain disorders that cause involuntary, debilitating and often painful movements, including twists and turns ...

Parkinson's & Movement disorders

New findings challenge current view on origins of Parkinson's disease

The neurodegeneration that occurs in Parkinson's disease is a result of stress on the endoplasmic reticulum in the cell rather than failure of the mitochondria as previously thought, according to a study in fruit flies. It ...

Neuroscience

Turn left! How myosin-Va helps direct neuron growth

Researchers at the RIKEN Brain Science Institute in Japan have discovered a protein complex that helps direct the growth of axons—the parts of neurons that make up our nerves, connecting our senses and muscles to the brain ...

Medical research

PERK-opathies: Stress mechanism underlying neurodegeneration

A major challenge in the field of neurodegeneration is the unclear understanding of neuronal dysfunction. Elucidation of these patho-mechanisms could result in the identification of novel therapeutic targets. In this article, ...

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