Cardiology

Novel lncRNA 'Caren' counteracts heart failure progression

A research collaboration based in Kumamoto University (Japan) has identified a novel lncRNA, Caren, that is abundantly expressed in cardiomyocytes. They showed that it enhances energy production by increasing the number of ...

Medical research

Normally harmless cell molecule triggers neuron death

A vital intermediate in normal cell metabolism is also, in the right context, a trigger for cell death, according to a new study from Wanli Liu and Yonghui Zhang of Tsinghua University, and Yong Zhang of Peking University ...

Medications

Treating aggressive breast cancer with an anti-diabetic drug

National University of Singapore researchers developed an approach to target highly resistant triple-negative breast cancers (TNBCs) by interfering with their energy production using cytotoxic gold-metformin prodrugs.

Health

Vitamin D deficiency may impair muscle function

Vitamin D deficiency may impair muscle function due to a reduction in energy production in the muscles, according to a mouse study published in the Journal of Endocrinology. Vitamin D deficient mice were found to have impaired ...

Oncology & Cancer

Bespoke neuroblastoma therapy weaponizes cell metabolism

Preclinical research from VCU Massey Cancer Center published recently in the Proceedings of the National Academy of Sciences shows that the combination of two existing drugs can exploit the metabolic 'hunger' of a particularly ...

Neuroscience

Study reveals immune driver of brain aging

Suppose Smokey the Bear were to go on a tear and start setting forest fires instead of putting them out. That roughly describes the behavior of certain cells of our immune system that become increasingly irascible as we grow ...

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