Neuroscience

Scientists uncover hexokinase 2's role in microglial activity

Microglia, the primary immune cells and key guardians of brain activity in the brain, can constantly monitor the microenvironment to maintain brain homeostasis. When subjected to acute depletion or under disease conditions, ...

Diseases, Conditions, Syndromes

A new way to fight diseases? Stop viruses from stealing nutrients

The immune system has long been touted as the body's primary defense against invading viruses, with the understanding that a strong immune response swiftly knocks out an infection while a weak one allows it to linger, leading ...

Diabetes

Widespread dysregulation of metabolism in type 2 diabetes

Using state of the art techniques, researchers from Uppsala University have shown that the metabolism in patients with type 2 diabetes and prediabetes was much more disturbed than previously known, and that it varied between ...

Diseases, Conditions, Syndromes

COVID-19: New energy for flagging immune cells

In severe COVID-19 patients, metabolism produces insufficient amounts of certain energy-rich compounds called ketone bodies. However, these energy carriers are needed by two important cell types in the immune system in order ...

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