Diseases, Conditions, Syndromes

COVID-19: New energy for flagging immune cells

In severe COVID-19 patients, metabolism produces insufficient amounts of certain energy-rich compounds called ketone bodies. However, these energy carriers are needed by two important cell types in the immune system in order ...

Arthritis & Rheumatism

How mitochondrial damage ignites the 'auto-inflammatory fire'

Mitochondria are self-contained organelles (they possess their own mini-chromosome and DNA) residing within cells and are charged with the job of generating the chemical energy needed to fuel functions essential to life and ...

Medical research

How the body uses fat to fight infection

New research from the University of East Anglia and Quadram Institute reveals how our immune cells use the body's fat stores to fight infection.

Immunology

Fighting multiple sclerosis with cold

In evolutionary biology, the "life history theory," first proposed in the 1950s, postulates that when the environment is favorable, the resources used by any organism are devoted for growth and reproduction. Conversely, in ...

Diseases, Conditions, Syndromes

Physical frailty syndrome: A cacophony of multisystem dysfunction

In the inaugural issue of the journal Nature Aging a research team led by aging expert Linda P. Fried, MD, MPH, dean of Columbia University Mailman School of Public Health, synthesizes converging evidence that the aging-related ...

Neuroscience

Myelin optimizes information processing in the brain

In a conversation, we can easily understand and distinguish individual words. In the brain, the temporal structure of speech with its rapid succession of sounds and pauses and its characteristic rhythm is encoded by electrical ...

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