Medications

Research helps pave way for newly approved use of drug

Following two decades of research on a group of rare diseases called hypereosinophilic syndrome at Cincinnati Children's Hospital Medical Center, the U.S. Food and Drug Administration has approved the drug Nucala (mepolizumab) ...

Immunology

Influenza A virus directly modulates eosinophil responses

Eosinophils residing in the airways of mice respond to influenza A virus (IAV) infection through alterations in surface expression of various markers necessary for migration and cellular immunity responses, according to research ...

Diseases, Conditions, Syndromes

FDA-approved drug effectively treats rare chronic immune disorders

A drug approved to treat a severe form of asthma dramatically improved the health of people with rare chronic immune disorders called hypereosinophilic syndromes (HES) in whom other treatments were ineffective or intolerable. ...

Medical research

Lean vs. obese adipose tissue cells

Eosinophils are a type of white blood cell that plays many roles in the body, including helping to maintain metabolic homeostasis, the steady state that ensures the body is adequately fueled and waste is eliminated.

Immunology

What causes asthma? What we know, don't know and suspect

Asthma is a chronic inflammatory disease of the lungs where the airways become so obstructed the sufferer struggles to breathe. It's vastly more prevalent in Western societies, and usually develops in childhood. But what ...

Immunology

New immune defenders added to blood cell

Our researchers have revealed the identities of new subsets of immune cells at the frontline of our body's defenses against infection.

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