Diseases, Conditions, Syndromes

FDA-approved drug effectively treats rare chronic immune disorders

A drug approved to treat a severe form of asthma dramatically improved the health of people with rare chronic immune disorders called hypereosinophilic syndromes (HES) in whom other treatments were ineffective or intolerable. ...

Medical research

Lean vs. obese adipose tissue cells

Eosinophils are a type of white blood cell that plays many roles in the body, including helping to maintain metabolic homeostasis, the steady state that ensures the body is adequately fueled and waste is eliminated.

Immunology

What causes asthma? What we know, don't know and suspect

Asthma is a chronic inflammatory disease of the lungs where the airways become so obstructed the sufferer struggles to breathe. It's vastly more prevalent in Western societies, and usually develops in childhood. But what ...

Immunology

New immune defenders added to blood cell

Our researchers have revealed the identities of new subsets of immune cells at the frontline of our body's defenses against infection.

Inflammatory disorders

Eosinophilic esophagitis may be due to missing protein

Scientists have discovered that the absence of a specific protein in cells lining the esophagus may cause inflammation and tissue damage in people with eosinophilic esophagitis (EoE). EoE affects as many as 150,000 people ...

Immunology

Can asthma be controlled with a vitamin supplement?

The shortness of breath experienced by the nearly 26 million Americans who suffer from asthma is usually the result of inflammation of the airways. People with asthma typically use albuterol for acute attacks and inhaled ...

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