The relationship between gene alterations and response to anti-PD-L1 with and without anti-CTLA-4 are not well characterized. Dr. N. Rizvi from Columbia University Medical Center in New York today presented an update from ...
Sep 9, 2019
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The Organoid group at the Hubrecht Institute has identified a new link between FBXW7 mutations and epidermal growth factor receptor (EGFR) signaling activity. The FBXW7 gene is commonly mutated in colorectal cancer and such ...
Mar 18, 2024
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In a new study, Yale researchers identify the targets in the human body to which pathogens transmitted by mosquitoes, ticks, and other vectors bind. Their findings, they say, could help address the rising threat of vector-borne ...
Jul 9, 2024
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Proteins that control cell growth are often mutated in cancer, and their aberrant signaling drives the wild proliferation of cells that gives rise to tumors. One such protein, the epidermal growth factor receptor (EGFR), ...
Apr 8, 2013
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Is the era of targeted therapy for breast cancer at hand? It could be, said experts at the Lester and Sue Smith Breast Center at Baylor College of Medicine – at least for a certain population of women.
Apr 8, 2013
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In a randomized phase III clinical trial conducted by the Radiation Therapy Oncology Group (RTOG), high-dose (HD), compared with standard-dose (SD), radiotherapy (RT) with concurrent chemotherapy (CT) did not improve overall ...
May 29, 2013
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Locally advanced squamous cell carcinoma of the head and neck is a potentially curable disease in nearly every patient at the time of diagnosis, yet despite the most aggressive efforts, up to 30-50 percent of patients may ...
Mar 7, 2013
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A new study finds substantial variation in the prevalence of triple-negative breast cancer among black women with breast cancer by birthplace in the United States. The prevalence of triple-negative breast cancer was highest ...
Jun 13, 2019
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A key protein known as claudin-2, which lines the intestinal epithelial cells of infant mice, helps them absorb more calcium from breast milk, according to a new study published in the journal Function titled "Maternal epidermal ...
Jul 25, 2023
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Surgical resection is considered a potentially curative treatment for pancreatic adenocarcinoma, however, the five year survival rate of patients receiving this treatment is less than 20 percent. Adjuvant treatment, therefore, ...
Jun 4, 2013
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