Genetics

DNA methylation changes in neurons of bipolar disorder patients

A research collaboration based in Kumamoto University, Japan, has revealed the DNA methylation status of gene transcriptional regulatory regions in the frontal lobes of patients with bipolar disorder (BD). The regions with ...

Health

No level of smoke exposure is safe during pregnancy

Nearly a quarter of pregnant women say they've been around secondhand smoke—in their homes, at work, around a friend or relative—which, according to new research, is linked to epigenetic changes—meaning changes to how ...

Health

Eight ways chemical pollutants harm the body

A new review of existing evidence proposes eight hallmarks of environmental exposures that chart the biological pathways through which pollutants contribute to disease: oxidative stress and inflammation, genomic alterations ...

Genetics

Lifestyle changes in pregnant women affect babies' genes

A study led by researchers at Lund University in Sweden showed a connection between lifestyle intervention in pregnant women with obesity and epigenetic alterations in the baby. The study is published in the journal Diabetes.

Oncology & Cancer

Scientists find one-two punch for preclinical cancer models

A one-two punch of changing gene expression, then deploying immune checkpoint inhibitors, shows promise in battling one of the most treatment-resistant types of cancer in preclinical models, according to a new publication ...

Genetics

Epigenetic changes precede onset of diabetes

Epigenetic changes in the islets of Langerhans of the pancreas can be detected in patients several years before the diagnosis of type 2 diabetes (T2D). These changes are responsible for the altered methylation activity of ...

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