Neuroscience

Research team develops new genetic-based epilepsy risk scores

An international team of researchers led by Cleveland Clinic has developed new genetic-based epilepsy risk scores which may lay the foundation for a more personalized method of epilepsy diagnosis and treatment. This analysis ...

Neuroscience

Team discovers one more piece to the autism puzzle

Mutations in a subunit of a receptor that binds the major inhibitory neurotransmitter GABAA in the brain have been linked, through a common mechanism, to epilepsy, autism and intellectual disability, researchers at Vanderbilt ...

Health

Study eyes air pollution, noise links to epilepsy

Epilepsy, a neurological disorder in which patients experience recurring seizures, can develop from a number of causes. Genetics plays a role, while some people develop it as a result of conditions like stroke, tumors or ...

Neuroscience

'Push-pull' dynamic in brain network is key to stopping seizures

Researchers at Carnegie Mellon University have discovered that the spreading of seizures through the brain can be suppressed depending on the amount of pressure within the brain, an important discovery that may revolutionize ...

Medical research

Astrocytes and epilepsy

The neurodevelopmental disorder Tuberous Sclerosis Complex (TSC) is characterized by often severe epilepsy, along with autism and psychiatric disorders. Astrocytes—star-shaped glial cells that serve multiple functions in ...

Neuroscience

Epilepsy surgery: The earlier the better, overview study shows

A person with drug resistant epilepsy who gets an early surgical intervention has a better chance of becoming seizure-free. This is shown in a systematic review and meta-analysis in which Sahlgrenska Academy researchers, ...

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Epilepsy

Epilepsy (from the Greek επιληψία /epili΄psia/ ) is a common chronic neurological disorder characterized by recurrent unprovoked seizures. These seizures are transient signs and/or symptoms of abnormal, excessive or synchronous neuronal activity in the brain. About 50 million people worldwide have epilepsy, with almost 90% of these people being in developing countries. Epilepsy is more likely to occur in young children, or people over the age of 65 years, however it can occur at any time. Epilepsy is usually controlled, but not cured, with medication, although surgery may be considered in difficult cases. However, over 30% of people with epilepsy do not have seizure control even with the best available medications. Not all epilepsy syndromes are lifelong – some forms are confined to particular stages of childhood. Epilepsy should not be understood as a single disorder, but rather as a group of syndromes with vastly divergent symptoms but all involving episodic abnormal electrical activity in the brain.

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