Medical research

Esophagus organoid holds promise for cancer research

Researchers at the University of Szeged in Hungary have demonstrated for the first time that an esophagus organoid successfully duplicates a vital function of that organ. The study is published in the American Journal of ...

Gastroenterology

New digital tool to better monitor Barrett's esophagus

A team including researchers from the Department of Energy's Oak Ridge National Laboratory has developed a digital tool to better monitor a condition known as Barrett's esophagus, which affects more than 3 million people ...

Oncology & Cancer

High immunoscores may help some win the battle against cancer

Cancerous tumors are made up of many more components than just malignant cells from the tissue of origin. Immune cells can be recruited to the tumor site and form what is known as the tumor microenvironment. A subset of these ...

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Esophageal cancer

Esophageal cancer is malignancy of the esophagus. There are various subtypes, primarily squamous cell cancer and adenocarcinoma. Squamous cell cancer arises from the cells that line the upper part of the esophagus. Adenocarcinoma arises from glandular cells that are present at the junction of the esophagus and stomach. Esophageal tumors usually lead to dysphagia (difficulty swallowing), pain and other symptoms, and are diagnosed with biopsy. Small and localized tumors are treated surgically with curative intent. Larger tumors tend not to be operable and hence cannot be cured; their growth can still be delayed with chemotherapy, radiotherapy or a combination of the two. In some cases chemo- and radiotherapy can render these larger tumors operable. Prognosis depends on the extent of the disease and other medical problems, but is fairly poor.

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