Oncology & Cancer

New drugs, new ways to target androgens in prostate cancer therapy

Prostate cancer cells require androgens including testosterone to grow. A recent review in the British Journal of Urology International describes new classes of drugs that target androgens in novel ways, providing alternatives ...

Psychology & Psychiatry

Estrogen alters memory circuit function in women with gene variant

Fluctuations in estrogen can trigger atypical functioning in a key brain memory circuit in women with a common version of a gene, NIMH scientists have discovered. Brain scans revealed altered circuit activity linked to changes ...

Oncology & Cancer

Team develops prognostic test for E2F4 in breast cancer

By looking at the expression levels of downstream genes of the regulators in breast cancer, investigators at Dartmouth Hitchcock's Norris Cotton Cancer Center (NCCC), led by Chao Cheng, PhD, have identified a gene signature ...

Medical research

Low testosterone raises risk of age-related functional disability

Elderly men with low levels of testosterone or other sex hormones have twice the likelihood of having declining physical function over two years' time compared with their peers who have the highest hormone levels, a new study ...

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