Oncology & Cancer

TrackSig: Unlocking the history of cancer through tumor evolution

A tumor is often made up of different cells, some of which have changed—or evolved—over time and gained the ability to grow faster, survive longer and potentially avoid treatment. These cells, which have an "evolutionary ...

Oncology & Cancer

Study tracks evolutionary transition to destructive cancer

Evolution describes how all living forms cope with challenges in their environment, as they struggle to persevere against formidable odds. Mutation and selective pressure—cornerstones of Darwin's theory—are the means ...

Immunology

A worm's-eye view of immunity

In 1998, scientists published the first complete genome of a multicellular organism—the worm Caenorhabditis elegans. At the same time, new technologies were emerging to help researchers manipulate genes and learn more about ...

Diseases, Conditions, Syndromes

'Defective' virus surprisingly plays major role in spread of disease

(Medical Xpress)—Defective viruses, thought for decades to be essentially garbage unrelated to the transmission of normal viruses, now appear able to play an important role in the spread of disease, new research by UCLA ...

Genetics

Following the footprints of positive selection

For decades, the human genome could only tell us what we already suspected about the evolution of certain traits. Researchers were able to trace the genetic origin stories of lactose tolerance (as opposed to lactose intolerance), ...

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