BRCA1 and BRCA2 genetic variants are a clinically important risk factor for the development of ovarian and breast cancer, and women who carry these variants have a lifetime risk of ovarian cancer of 39%-44% and 11%-17%, respectively.
Aug 12, 2019
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Elizabeth Kough had been pregnant before. She knew how it felt. She just couldn't believe it had happened this time.
May 31, 2019
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Maintenance treatment with the PARP inhibitor rucaparib (Rubraca) was well tolerated and provided clinical responses among patients with advanced BRCA- or PALB2-mutated pancreatic cancer sensitive to platinum-based chemotherapy, ...
Apr 02, 2019
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Ovarian cancer claims the highest mortality rate of all gynecologic cancers, as high as 70 percent—in part because the disease is rarely detected earlier than stage 3 or 4. When the disease is discovered early in its development, ...
Oct 31, 2018
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New research from the University of Illinois at Chicago shows that cancer cells in the fallopian tube affect normal chemical signaling between reproductive tissues and stimulate the release of norepinephrine, a small molecule ...
Oct 09, 2018
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Between 1% and 10% of Australian women have endometriosis, a condition where the tissue that normally lines the uterus, the endometrium, grows outside the womb.
Sep 07, 2018
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Surgery is a major part of ovarian cancer treatment, but it can be a blunt tool.
Aug 17, 2018
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More than two-thirds of women with ovarian cancer have high-grade serous carcinoma (HGSC). Up to 90 percent of HGSCs are not detected until they are beyond the ovaries or fallopian tubes, at which point it may not be possible ...
Aug 13, 2018
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(HealthDay)—Essure implants used in female sterilization have come under fire in recent years, with women reporting a wide array of problems to the U.S. Food and Drug Administration.
Jan 23, 2018
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Screening for tumor cells in the fallopian tubes of women at high-risk for ovarian cancer may help detect the cancer years before it develops further, suggests a new study co-led by researchers at Penn Medicine and published ...
Oct 26, 2017
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