Medical research

Disarming a blood-clotting protein prevents gum disease in mice

Blocking function of a blood-clotting protein prevented bone loss from periodontal (gum) disease in mice, according to research led by scientists at the National Institute of Dental and Craniofacial Research (NIDCR), part ...

Alzheimer's disease & dementia

New study reveals how blood triggers brain disease

In patients with neurological diseases like Alzheimer's disease and multiple sclerosis, immune cells in the brain known as microglia that normally fulfill beneficial functions become harmful to neurons, leading to cognitive ...

Immunology

New immunotherapy targeting blood-clotting protein

Normally, the blood protein fibrin does not enter the brain. But in several neurological disorders, the blood-brain barrier—which keeps large molecules in the blood from entering the brain—becomes abnormally permeable, ...

Cardiology

How and why blood clots shrink

Blood clotting is the "Jekyll and Hyde" of biological processes. It's a lifesaver when you're bleeding, but gone awry, it causes heart attacks, strokes and other serious medical problems. If a clot grows too big, pieces dislodged ...

Neuroscience

A new therapeutic target for traumatic brain injury

For the roughly 1.5 million Americans per year who survive a traumatic brain injury, health outcomes vary widely. Not only can these injuries lead to a loss of coordination, depression, impulsivity, and difficulty concentrating, ...

Medical research

Novel regulatory mechanism of blood clotting discovered

Hemostasis is vital to prevent excessive blood loss. However, there is an increased risk for thrombosis if there is an excessive reaction and uncontrolled formation of fibrin. In a new study published in Nature Cardiovascular ...

Medical research

Reasons for severe bleeding in hemophilia revealed

New insights into what causes uncontrollable bleeding in hemophilia patients are provided in a study published by Cell Press on November 20th in the Biophysical Journal. By revealing that blood clots spread in traveling waves ...

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