New preclinical research suggests the potential utility of BPN14770, a selective PDE4D inhibitor currently under development by Tetra Discovery Partners as a prospective treatment for memory and cognitive problems associated ...
Nov 7, 2017
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A potential new therapeutic strategy for treating Fragile X syndrome is detailed in a new report appearing in the current issue of Biological Psychiatry, from researchers led by Dr. Lucia Ciranna at University of Catania ...
Nov 29, 2012
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An extensive study of country-specific risk of hip fracture and 10-year probability of a major fragility fracture has revealed a remarkably large geographic variation in fracture risk. Even accounting for possible errors ...
Mar 21, 2012
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A collaboration between scientists in Belgium, the United States, Norway, France and the UK has resulted in a study that sheds light on the neural mechanisms of fragile X syndrome. This genetic disorder, which affects males ...
May 5, 2017
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The cause of fragile X syndrome (FXS), the most common inherited intellectual disability, is easy to see in the lab. Under electron microscopy, an affected X chromosome exhibits a deformed tip that gives the disorder its ...
Oct 23, 2020
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Is the occurrence of a fragility fracture - where Medicare beneficiaries broke a hip, wrist or shoulder - a missed opportunity to reduce exposure to prescription drugs associated with fracture risk?
Aug 22, 2016
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Researchers at the European Congress of Osteoporosis & Osteoarthritis in Bordeaux have presented new data* which shows that the economic burden of fragility fractures in the 27 member states of the European Union far exceeds ...
Mar 23, 2012
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Osteoporosis, a disease of progressive bone loss, affects 70 percent of the U.S. population older than age 50: one in two women—and one in five men. These individuals are at risk for fragility fractures, a break that results ...
Oct 8, 2015
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A class of FDA-approved cancer drugs may be able to prevent problems with brain cell development associated with disorders including Down syndrome and Fragile X syndrome, researchers at the University of Michigan Life Sciences ...
May 19, 2015
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Four years ago, Janelly Martinez-Amador was confined to a bed, unable to move even an arm or lift her head. At age 3, the fragile toddler had the gross motor skills of a newborn and a ventilator kept her alive.
Apr 24, 2013
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