Opioids are powerful painkillers, but their use is hindered because patients become tolerant to them, requiring higher and higher doses, and overdoses can cause respiratory depression and death. A recent study from researchers ...
Aug 24, 2021
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Pharmacologists are working to help mitigate the detrimental side effects of opiates, including addiction, respiratory depression, constipation and alcohol use. Many pharmacologists are doing this by developing drugs that ...
Aug 11, 2021
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Researchers from the G-protein-coupled receptor-based drug development research group at the Hospital del Mar Medical Research Institute (IMIM) have been able to verify, with a degree of precision never before achieved, ...
Jul 29, 2021
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An LMU team has clarified how a receptor which is involved in the regulation of vital physiological processes senses the mechanical forces that act on blood vessels. The findings could suggest new therapies for diseases of ...
Jan 31, 2020
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New research from Cornell University details how two highly lethal viruses have greater pathogenic potential when their proteins are combined.
Aug 13, 2019
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Researchers from Karolinska Institutet in Sweden have found a protein that is a critical regulator in the development of fatty liver disease in mice, according to a study published in the journal Nature Communications.
Apr 11, 2019
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While investigating why cholesterol-lowering drugs called statins cause negative side effects such as blurred vision, short-term memory loss or increased risk for diabetes, cellular chemists at The University of Toledo discovered ...
Mar 19, 2019
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New research on how cancer mutations influence a certain type of receptor on the cell membrane opens the way for the development of tailored drugs for certain cancers, such as rectal cancer and lung cancer. This, according ...
Feb 11, 2019
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Receptors for the messenger molecule serotonin can be modified in such a way that they can be activated by light. Together with colleagues, neuroscientists from the Ruhr-Universität Bochum (RUB) report on this finding in ...
Apr 7, 2014
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A newly found understanding of receptor signaling may have revealed a better way to design drugs. A study from Nationwide Children's Hospital suggests that a newly identified group of proteins, alpha arrestins, may play a ...
Dec 10, 2012
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