A team of scientists from the Scripps Research Institute, collaborating with members of the drug discovery company Receptos, has created the first high-resolution virtual image of cellular structures called S1P1 receptors, ...
Feb 16, 2012
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Pharmacologists are working to help mitigate the detrimental side effects of opiates, including addiction, respiratory depression, constipation and alcohol use. Many pharmacologists are doing this by developing drugs that ...
Aug 11, 2021
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A team including scientists from The Scripps Research Institute (TSRI), the University of North Carolina at Chapel Hill and the Chinese Academy of Sciences has determined and analyzed the high-resolution atomic structures ...
Mar 21, 2013
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Researchers from Hefei University of Technology in China have recently published an exhaustive review in the Journal of Medicinal Chemistry on emerging roles of small kinase inhibitors in the treatment of diseases. In contrast ...
Scientists at Scripps Research have comprehensively mapped how a key class of proteins within cells regulates signals coming in from cell surface receptors.
Oct 2, 2020
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Strategies to treat pain without triggering dangerous side effects such as euphoria and addiction have proven elusive. For decades, scientists have attempted to develop drugs that selectively activate one type of opioid receptor ...
May 3, 2023
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A new research paper has been published in Aging (Aging-US), titled "Effect of Humanin G (HNG) on inflammation in age-related macular degeneration (AMD)."
May 31, 2022
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A new targeted therapy for prostate cancer halts tumor growth in animals with advanced prostate cancer that is resistant to hormone therapy, a new study finds. The results will be presented Saturday at The Endocrine Society's ...
Jun 6, 2011
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Like a bank robber on the lam, Gpr182 had assumed a variety of identities over several decades: G10D, HrhAMR, Gamrh, 7TMR, ADMR. Unable to put a finger on what exactly the gene does, scientists largely left it alone. The ...
Jan 20, 2017
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Researchers from Karolinska Institutet in Sweden have found a protein that is a critical regulator in the development of fatty liver disease in mice, according to a study published in the journal Nature Communications.
Apr 11, 2019
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