Through research in mice, scientists have found that proteins at the blood-brain barrier pump out riluzole, the only FDA-approved drug for ALS, or Lou Gehrig's disease, limiting the drug's effectiveness. However, when the ...
Dec 1, 2014
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Researchers at Johns Hopkins Medicine have transformed skin cells from patients with Lou Gehrig's disease, or amyotrophic lateral sclerosis (ALS), into brain cells affected by the progressive, fatal disease and deposited ...
Apr 14, 2015
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Researchers at the USF Health Morsani College of Medicine, located at the University of South Florida, successfully tested a protein that has the potential to aid in the development of a protein-based therapy for patients ...
Oct 4, 2022
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Approximately 31,000 people are living with amyotrophic lateral sclerosis (ALS) in the United States, with an average of 5,000 new cases every year, according to the Centers for Disease Control and Prevention.
May 8, 2024
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A team led by investigators at Massachusetts General Hospital (MGH) has shown that people living with amyotrophic lateral sclerosis (ALS), or Lou Gehrig's disease, who carry a mutation in the C9orf72 gene exhibit elevated ...
Nov 15, 2021
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Increasing the levels of the anti-aging protein hormone Klotho improves the neurological deficits and prolongs life span in an experimental model with Amyotrophic Lateral Sclerosis (ALS). In addition, brain immune cells called ...
Jun 27, 2019
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Advocacy groups are pressing U.S. federal regulators to fast-track approval of an experimental drug treatment for the deadly neurological disease ALS (amyotrophic lateral sclerosis), with a decision expected this week.
Mar 28, 2022
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Measuring changes in certain proteins—called biomarkers—in people with amyotrophic lateral sclerosis may better predict the progression of the disease, according to scientists at Penn State College of Medicine.
Dec 17, 2013
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A recent collaborative research endeavor, published in Cell Reports Medicine, highlights a promising therapeutic avenue for amyotrophic lateral sclerosis (ALS). Led by researchers from Ben-Gurion University of the Negev in ...
May 29, 2024
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Every year roughly 1,000 Canadians are diagnosed with amyotrophic lateral sclerosis (ALS, also known as Lou Gehrig's disease). Some 4,000 Canadians are currently living with the disease.
May 14, 2024
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