Northwestern Medicine investigators have shown that inhibiting a mutated gene can reduce seizure activity in adult-type diffuse gliomas, according to a study published in the Journal of Clinical Investigation.
Jun 1, 2023
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4
Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, is a fatal motor neuron disease that causes people to gradually lose control of their muscles. There is no cure, and current treatments focus on reducing ...
Jun 1, 2023
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116
The low blood oxygen levels of obstructive sleep apnea (OSA) cause widespread changes in gene activity throughout the day, according to a new study in the open-access journal PLOS Biology by David Smith of Cincinnati Children's ...
May 30, 2023
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31
Our bodies make blood in a specialized niche—a "nursery" within our bone marrow that nurtures blood stem cells so they can replicate and make different kinds of blood cells. The lab of Leonard Zon, MD, has even shown how ...
May 24, 2023
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93
Strokes cause numerous changes in gene activity in affected small blood vessels in the brain, and these changes are potentially targetable with existing or future drugs to mitigate brain injury or improve stroke recovery, ...
Apr 14, 2023
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82
A major new study in the journal Nature reveals a 'traffic light' mechanism controlling genetic activity within cells—a system which could potentially be targeted by cancer drugs already in development.
Mar 1, 2023
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49
A UCL-led research team has, for the first time, identified a specific region of chromosome 21, which causes issues with memory function and anxiety in a mouse that models Down syndrome, a finding that provides valuable new ...
Feb 23, 2023
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15
"Use it or lose it" goes the adage, applied liberally to everything from our muscles to our minds, especially as we age.
Feb 15, 2023
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1211
When an embryo is formed, its genes—donated by a fertilizing sperm and egg—are silent. Somehow, at an early stage of development, embryo genes must be switched on. Without this vital 'genes on' switch in the embryo, none ...
Feb 1, 2023
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48
Researchers at the University of Pittsburgh School of Medicine, U.S. present the first evidence of 12-hour cycles of gene activity in the human brain. Published in the open access journal PLOS Biology on January 24, the study ...
Jan 24, 2023
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