Dysfunction in dopamine signaling profoundly changes the activity level of about 2,000 genes in the brain's prefrontal cortex and may be an underlying cause of certain complex neuropsychiatric disorders, such as schizophrenia, ...
Jul 21, 2014
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Approximately 98 percent of the human genome is made up of noncoding DNA, including enhancers, promoters, and other elements that regulate gene activity. The methods for studying these regions tend to be expensive, labor-intensive, ...
Dec 21, 2018
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Researchers have identified a gene that promotes muscle strength when switched on by physical activity, unlocking the potential for the development of therapeutic treatments to mimic some of the benefits of working out.
Jul 25, 2022
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Immune cells in the brains of people who had Alzheimer's disease appear to behave differently than those who had healthy brains for their age, according to an analysis of the cells' gene activity.
Aug 10, 2023
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An international team of researchers, led by scientists at the University of California, San Diego and Yale University schools of medicine, have identified a form of autism with epilepsy that may potentially be treatable ...
Sep 6, 2012
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Keeping egg cells in stasis during childhood is a key part of female fertility. New research published today in Nature Structural and Molecular Biology sheds some light on the role of epigenetics in placing egg cells into ...
Jan 1, 2018
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Following up on findings from a an earlier genome-wide association study (GWAS) of type 2 diabetes (T2D) in Latinos, researchers from the Broad Institute of MIT and Harvard and Massachusetts General Hospital (MGH) traced ...
Jun 30, 2017
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Pioneering research into the mechanisms controlling gene activity in the brain could hold the key to understanding Alzheimer's disease and might help identify effective treatments in the future.
Oct 22, 2018
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Using a technique that silences genes promoting infection, researchers have developed a novel, topically-applied molecular microbicide capable of preventing HIV transmission. The microbicide is predicted to have long-lasting ...
May 16, 2011
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Oncolytic viruses quickly infect and kill cancer stem cells, which may provide a treatment for tumors that are resistant to conventional chemotherapy and radiation, particularly pancreatic cancer, according to new research ...
May 9, 2011
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