Medical research

Defining the role of HDAC6 in regulating heart stiffness

Researchers at the University of Colorado School of Medicine have discovered an enzyme that regulates heart stiffness, setting the stage for developing novel treatments for heart failure.

Genetics

Study offers new insights on gene activity and addiction

Researchers at North Carolina State University have demonstrated that neuron-like cells derived from human stem cells can serve as a model for studying changes in the nervous system associated with addiction. The work sheds ...

Diseases, Conditions, Syndromes

Malaria parasite ticks to its own internal clock

When a person gets malaria, a rhythmic dance takes place inside their body. The disease's telltale signs—cyclical fevers and chills—are caused by successive broods of parasites multiplying in sync inside red blood cells, ...

Genetics

Form of severe malnutrition linked to DNA modification

A group led by researchers at Baylor College of Medicine has identified significant differences at the epigenetic level—the chemical tags in DNA that help regulate gene expression—between two clinically distinct forms ...

Genetics

A look at how colds and chronic disease affect DNA expression

We're all born with a DNA sequence that encodes (in the form of genes) the very traits that make us, us—eye color, height, and even personality. We think of those genes as unchanging, but in reality, the way they are expressed, ...

Cardiology

ASH: High-dose gene transfer beneficial in severe hemophilia A

(HealthDay)—For men with severe hemophilia A, high-dose factor VIII gene transfer is associated with sustained normalization of factor VIII activity levels, according to a study published online Dec. 9 in the New England ...

Medical research

'CYCLOPS' algorithm spots daily rhythms in cells

Humans, like virtually all other complex organisms on Earth, have adapted to their planet's 24-hour cycle of sunlight and darkness. That circadian rhythm is reflected in human behavior, of course, but also in the molecular ...

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