Genetics

Gene variants increase risk of Addison's disease

Variants of nine genes increase the risk of developing Addison's disease, a rare disease in which the immune system attacks the adrenal glands. That is according to the largest genetic study to date on patients with Addison's ...

Oncology & Cancer

Scientists find one-two punch for preclinical cancer models

A one-two punch of changing gene expression, then deploying immune checkpoint inhibitors, shows promise in battling one of the most treatment-resistant types of cancer in preclinical models, according to a new publication ...

Genetics

Study identifies group of genes with altered expression in autism

Autism has long been associated only with behavioral and environmental factors, but the role of genetics in its development is now increasingly evident. Some 100 genes have been found to play a role in autism spectrum disorder, ...

Diseases, Conditions, Syndromes

COVID-19: Exercise may protect against deadly complication

Regular exercise may reduce the risk of acute respiratory distress syndrome, a major cause of death in patients with the COVID-19 virus, a top exercise researcher reports. He is urging people to exercise based on his findings, ...

Dentistry

Study reveals how too much fluoride causes defects in tooth enamel

Exposing teeth to excessive fluoride alters calcium signaling, mitochondrial function, and gene expression in the cells forming tooth enamel—a novel explanation for how dental fluorosis, a condition caused by overexposure ...

Neuroscience

New roles found for Huntington's disease protein

A Duke University research team has identified a new function of a gene called huntingtin, a mutation of which underlies the progressive neurodegenerative disorder known as Huntington's Disease.

Diseases, Conditions, Syndromes

Finding the genes that turn on Japanese encephalitis

Investigators have identified the specific genes that become overactive as a result of nerve cell infection with Japanese encephalitis virus. The genes activate cell receptors and signaling proteins that attract immune cells ...

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