Gene editing therapies, including CRISPR-Cas systems, offer the potential to correct mutations causing inherited retinal degenerations, a leading cause of blindness. Technological advances in gene editing, continuing safety ...
Jan 20, 2021
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Use of thyroid hormone to boost hepatocyte proliferation enhanced the efficiency of CRISPR/Cas9-mediated gene correction in the mouse liver. This dietary induction of hepatocyte regeneration may be a viable clinical strategy ...
Nov 10, 2020
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The potential for treating cystic fibrosis (CF) using mRNA therapies or CRISPR gene editing is possible regardless of the causative mutation. CF clinical trials showing that a genotype-agnostic gene therapy for CF is possible ...
Oct 9, 2020
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The CRISPR genome editing technique promises to be a "transformative leap" in genetic engineering and therapy, affecting almost every area of medicine. That includes plastic surgery, with potential advances ranging from prevention ...
Oct 30, 2018
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A new study that compared six of the most promising adeno-associated viral (AAV) gene therapy vectors in human retinal organoid models showed clear distinctions in the efficiency of gene transfer to both retinal pigment epithelial ...
Jun 13, 2018
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Recombinant adeno-associated virus (rAAV) vectors for delivering therapeutic genes have demonstrated their safety in multiple diseases and clinical settings over the years and are a proven and effective tool that can be used ...
Mar 20, 2017
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The National Academy of Sciences and National Academy of Medicine issued a 258-page report Tuesday (Feb. 14) focused on human genome editing. It lays out principles and recommendations for the U.S. government and governments ...
Feb 14, 2017
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University of Wisconsin-Madison engineers have developed methods to observe gene editing in action, and they're putting those capabilities to work to improve genetic engineering techniques.
Jan 24, 2017
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Since its development, CRISPR technology has been applied a range of scientific inquiries, spanning from the genomic editing of Florida orange crops to Zebrafish. In work recently published in PLOS Pathogens, Robert Jan Lebbink ...
Aug 5, 2016
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