An international team of researchers has identified specific bacteria in the gut that are associated with both mice and humans developing an addiction to food that can lead to obesity. They have also identified bacteria that ...
Jun 26, 2024
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Understanding the molecular characteristics of cancer that impact patient outcomes is essential to identifying novel treatment strategies for the most intractable pediatric malignancies. Many of these diseases are difficult ...
Jun 26, 2024
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Transcription factors (TFs) are proteins that bind to specific DNA sequences, regulating the transcription of genetic information from DNA to messenger RNA (mRNA). These proteins play a pivotal role in the regulation of gene ...
Scientists at the Victor Chang Cardiac Research Institute in Australia have produced a first of its kind integrated map of heart cells which unlocks the process of cardiac fibrosis—a major cause of heart failure.
Jun 21, 2024
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What causes food allergies to develop? There's compelling evidence that suggests imbalances of the gut microbiome could be to blame, creating inflammation of the intestinal tract and a gut environment that's prone to food ...
Jun 21, 2024
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A new aging atlas gives scientists an in-depth view of how individual cells and tissues in worms age and how different lifespan-extending strategies might stop the clock. The work is published in the journal Nature Aging.
Jun 17, 2024
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An unsuspected gene, Glis2, has been found to be a target of polycystic kidney disease (PKD) signaling in preclinical models.
Jun 13, 2024
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Babies born after exposure to famine in-utero show signs of accelerated aging six decades later, according to a study at Columbia University Mailman School of Public Health and the Robert N. Butler Columbia Aging Center. ...
Jun 12, 2024
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Short-term space travel causes many of the same molecular and physiologic changes as long-term space missions, but most reverse within months of returning to Earth. Yet, those changes that are longer-lasting and distinct ...
Jun 11, 2024
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Determining the genetic and epigenetic factors that influence brain folding is the objective of the latest study co-led by the Neurogenesis and Cortical Expansion laboratory, directed by researcher Víctor Borrell at the ...
Jun 11, 2024
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Gene expression is the process by which information from a gene is used in the synthesis of a functional gene product. These products are often proteins, but in non-protein coding genes such as rRNA genes or tRNA genes, the product is a functional RNA.
Several steps in the gene expression process may be modulated, including the transcription, RNA splicing, translation, and post-translational modification of a protein. Gene regulation gives the cell control over structure and function, and is the basis for cellular differentiation, morphogenesis and the versatility and adaptability of any organism. Gene regulation may also serve as a substrate for evolutionary change, since control of the timing, location, and amount of gene expression can have a profound effect on the functions (actions) of the gene in the organism.
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