Obstetrics & gynaecology

Acid reflux drug is a surprising candidate to curb preterm birth

Lansoprazole, an over-the-counter acid reflux drug that is often taken by pregnant women, may be a promising therapy to reduce preterm birth, according to a computational drug repurposing study that also tested several of ...

Diseases, Conditions, Syndromes

New method predicts individual response to Ebola infection

Not everyone who catches Ebola dies of the hemorrhagic virus infection. Some people mount a robust immune defense and recover fully. Yet risk factors for susceptibility to infection and disease severity remain poorly understood.

Medications

Histamine: an unexpected defender against heart and kidney damage

Chronic kidney disease and heart failure are critical medical problems worldwide, and are closely associated in a phenomenon known as "cardiorenal syndrome." The relationship between kidney dysfunction and heart dysfunction ...

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Gene expression

Gene expression is the process by which information from a gene is used in the synthesis of a functional gene product. These products are often proteins, but in non-protein coding genes such as rRNA genes or tRNA genes, the product is a functional RNA.

Several steps in the gene expression process may be modulated, including the transcription, RNA splicing, translation, and post-translational modification of a protein. Gene regulation gives the cell control over structure and function, and is the basis for cellular differentiation, morphogenesis and the versatility and adaptability of any organism. Gene regulation may also serve as a substrate for evolutionary change, since control of the timing, location, and amount of gene expression can have a profound effect on the functions (actions) of the gene in the organism.

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