Genetics

Breakthrough in understanding male infertility

Hope has emerged for infertile men as scientists at Newcastle University have understood the importance of a gene in regulating the production of fully-functioning sperm.

Neuroscience

Mice pass on brain benefits of enriched upbringing to offspring

Mice growing up in a basic cage maintain lifelong visual cortex plasticity if their parents were raised in an environment that promoted social interaction and physical and mental stimulation, according to a multigenerational ...

Health

'Safe' herbicide in Australian water affects male fertility

The last 50 years has seen a rapid decline in male reproductive health. Decreased sperm counts, increased rates of testicular cancer and a range of malformations in male genitalia have been reported in industrialised countries ...

Psychology & Psychiatry

Epigenetics contribute to male and female differences in fear memory

In a mouse model of traumatic memory, male mice recall fear-related memories better than female mice, according to a study in Biological Psychiatry. The difference between sexes was attributed to a gene important for creating ...

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Gene expression

Gene expression is the process by which information from a gene is used in the synthesis of a functional gene product. These products are often proteins, but in non-protein coding genes such as rRNA genes or tRNA genes, the product is a functional RNA.

Several steps in the gene expression process may be modulated, including the transcription, RNA splicing, translation, and post-translational modification of a protein. Gene regulation gives the cell control over structure and function, and is the basis for cellular differentiation, morphogenesis and the versatility and adaptability of any organism. Gene regulation may also serve as a substrate for evolutionary change, since control of the timing, location, and amount of gene expression can have a profound effect on the functions (actions) of the gene in the organism.

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