Alzheimer's disease & dementia
Changes in genetic function in the brain linked to Alzheimer's
Changes in the epigenome, a structure that controls the function of genes, were found in the brains of Alzheimer's patients.
Apr 20, 2012
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Page 20 - News tagged with gene target
Oncology & Cancer
Scientists find new breast cancer genes, rewrite rulebook
Scientists at the BC Cancer Agency and University of British Columbia have identified new breast cancer genes that could change the way the disease is diagnosed and form the basis of next-generation treatments.
Apr 18, 2012
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Oncology & Cancer
Target set on cancer gene MCL1
A research team pursuing one of the most commonly altered genes in cancer has laid a critical foundation for understanding this gene that could point the way toward developing drugs against it. A recent study of cancer genetics ...
Apr 16, 2012
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Oncology & Cancer
KRAS gene mutation and amplification status affects sensitivity to antifolate therapy
Testing patients with non-small cell lung cancer for both mutations and amplifications of the KRAS gene prior to therapy may help to predict response to treatment with antifolates, according to the updated results of a preclinical ...
Apr 4, 2012
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Autism spectrum disorders
Study identifies gene expression abnormalities in autism
A study led by Eric Courchesne, PhD, director of the Autism Center of Excellence at the University of California, San Diego School of Medicine has, for the first time, identified in young autism patients genetic mechanisms ...
Mar 22, 2012
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Oncology & Cancer
Tranylcypromine antidepressant shows promise as cancer treatment
A retinoid called all-trans retinoic acid (ATRA), which is a vitamin A-derivative, is already used successfully to treat a rare sub-type of acute myeloid leukemia (AML), however this drug has not been effective for the more ...
Mar 11, 2012
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Oncology & Cancer
Aurora-A hinders tumor-suppressor to allow chemotherapy resistance
A protein abundantly found in treatment-resistant cancers holds an important tumor-suppressor out of the cell nucleus, where it would normally detect DNA damage and force defective cells to kill themselves, a team of scientists ...
Feb 27, 2012
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Genetics
Unraveling why children with Down syndrome have increased leukemia risk
Children with Down syndrome (DS) have an increased risk of developing leukemia, in particular acute megakaryoblastic leukemia (AMKL) and acute lymphoblastic leukemia (ALL). Through their studies in a mouse model of DS, a ...
Feb 22, 2012
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Oncology & Cancer
Role of known cancer gene in ovarian cancer investigated
The role of a known cancer-causing gene in the development of the most lethal type of ovarian cancer is being investigated by researchers from the Walter and Eliza Hall Institute after they were awarded a Cure Cancer Australia ...
Feb 14, 2012
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Neuroscience
Researchers increase understanding of gene's potentially protective role in Parkinson's
Treatments for Parkinson's disease, estimated to affect 1 million Americans, have yet to prove effective in slowing the progression of the debilitating disease.
Feb 7, 2012
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