A research team led by the Icahn School of Medicine at Mount Sinai (Icahn Mount Sinai) has built the first cellular model to depict the evolution of acute myeloid leukemia (AML), from its early to late stages. By using gene ...
Feb 10, 2021
0
50
Among patients with lung cancer from Latin America, genomic and ancestry analyses revealed that Native American ancestry was associated with increased mutations in the EGFR gene, independent of smoking status, according to ...
Dec 2, 2020
0
2
A Swedish study has identified 17 new genes that could be targeted for treatment of psoriasis and eczema, two common hereditary skin diseases with no cure.
Oct 27, 2020
0
56
A novel agent that targets a mutated form of the KRAS gene—the most commonly altered oncogene in human cancers and one long considered "undruggable"—shrank tumors in most patients in a clinical trial with manageable side ...
Oct 25, 2020
0
17
Researchers at the Institut de Recerca Sant Joan de Déu (IRSJD) in collaboration with those at Center for Genomic Regulation (CRG) have discovered that RING1B is a critical gene for the development of Ewing sarcoma, a rare ...
Oct 23, 2020
0
52
The potential for treating cystic fibrosis (CF) using mRNA therapies or CRISPR gene editing is possible regardless of the causative mutation. CF clinical trials showing that a genotype-agnostic gene therapy for CF is possible ...
Oct 9, 2020
0
1
Researchers from Children's Hospital of Philadelphia (CHOP) have shown there may be key genetic differences in the causes of attention-deficit hyperactivity disorder (ADHD) between African Americans and people of European ...
Sep 22, 2020
0
52
Atypical teratoid rhabdoid tumors (ATRT) are a rare, fast-growing form of brain cancer that usually strikes children three years and younger, though they can occur in older children and adults. There are multiple treatments, ...
Sep 10, 2020
0
48
A new publication by scientists from Children's Medical Research Institute has challenged one of the foundations of the gene therapy field and will help to improve strategies for treating serious genetic disorders of the ...
Sep 9, 2020
0
94
Following reports in June that the cheap steroid drug dexamethasone could help treat patients severely ill with COVID-19, scientists and clinicians urged caution. They were careful to highlight the need for further study ...
Sep 8, 2020
0
8
