City of Hope today announced study results of a Phase 2 clinical trial showing monotherapy with sotorasib resulted in anti-tumor activity and a favorable benefit-risk profile among heavily pretreated patients with advanced ...
Dec 15, 2021
0
3
Scientists have discovered that gene therapy and the diabetes drug metformin may be potential treatments for late-onset retinal degeneration (L-ORD), a rare, blinding eye disease. Researchers from the National Eye Institute ...
Dec 9, 2021
0
60
Over a decade ago, UCLA physician-scientists began using a pioneering gene therapy they developed to treat children born with a rare and deadly immune system disorder. They now report that the effects of the therapy appear ...
Oct 15, 2021
0
241
A common mutation in gliomas sensitizes them to immunotherapy, a finding that researchers believe could have broader therapeutic implications for all glioma patients.
Sep 29, 2021
0
51
After several decades of pre-clinical development, cell- and gene-based therapies for Parkinson's disease (PD) are now actively being explored. In this special supplement to the Journal of Parkinson's Disease, "Repairing ...
Sep 24, 2021
0
21
Genetic muscle diseases lead to progressive muscle wasting and often early death, with few treatment options and no cure. Some gene therapies that use a harmless virus to deliver a functioning copy of a disease-causing gene ...
Sep 9, 2021
0
244
Lung cancer is the leading cause of cancer death among men and women in the United States, regardless of ethnicity. Non-small cell lung cancer is the most common form of the disease, accounting for 84% of all diagnoses. One ...
Aug 3, 2021
0
348
Preliminary results of a clinical trial for Crigler-Najjar syndrome point to gene therapy as a potential alternative treatment for this life-threatening liver disease.
Jul 23, 2021
0
1
A novel method of gene therapy is helping children born with a rare genetic disorder called AADC deficiency that causes severe physical and developmental disabilities. The study, led by researchers at The Ohio State University ...
Jul 12, 2021
0
46
Preliminary results from the European gene therapy trial for Crigler-Najjar syndrome, conducted by Genethon in collaboration with European network CureCN, were presented at the EASL (European Association for the Study of ...
Jun 28, 2021
0
4
