The last year has seen milestones in the gene therapy field, with FDA approvals to treat cancer and an inherited blinding disorder. New findings from a team led by University of Pennsylvania vision scientists, who have in ...
Aug 20, 2018
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OHSU scientists have discovered a naturally occurring disease in monkeys that mimics a deadly childhood neurodegenerative disorder in people—a finding that holds promise for developing new gene therapies to treat Batten ...
Jul 27, 2018
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In the maze of our brains, there are various pathways by which neural signals travel. These pathways can go awry in patients with neurological and psychiatric diseases and disorders, such as epilepsy, Parkinson's, and obsessive-compulsive ...
Jul 9, 2018
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Therapeutic use of gene editing with the CRISPR-Cas9 technique may inadvertently increase the risk of cancer, according to a new study from Karolinska Institutet, Sweden, and the University of Helsinki, Finland, published ...
Jun 11, 2018
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Melanoma, a relatively rare but deadly skin cancer, has been shown to switch differentiation states—that is, to regress to an earlier stage of development—which can lead it to become resistant to treatment. Now, UCLA ...
Apr 12, 2018
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Gene therapy has shown promise in treating inherited genetic diseases, but a major issue that has frustrated scientists remains: Replacing a "bad" gene with a healthy one often is a short-lived fix. Typically, the healthy ...
Apr 2, 2018
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UC San Francisco scientists have uncovered a common genetic driver of aggressive meningiomas, which could help clinicians detect such dangerous cancers earlier and lead to new therapies aimed at curing these difficult-to-treat ...
Mar 28, 2018
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Researchers from the University of Pennsylvania have developed a gene therapy that successfully treats a form of macular degeneration in a canine model. The work sets the stage for translating the findings into a human therapy ...
Mar 5, 2018
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In a first-of-its-kind clinical study, Baylor College of Medicine evaluated the safety, survival and anti-tumor activity of tumor-specific T cells rendered resistant to transforming growth factor β (TGFβ), in patients with ...
Jan 26, 2018
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A new type of gene therapy delivered using a virus could protect healthy tissues from the harmful side-effects of radiotherapy after cancer treatment, a new study reports.
Jan 24, 2018
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