Obstetrics & gynaecology

Maternal gum disease may be connected to preterm birth

Women with preterm births may be more likely to have gum disease compared to those with full-term births, according to research presented at EuroPerio10, the world's leading congress in periodontology and implant dentistry ...

Genetics

A person's height impacts their risk of multiple diseases

Whether tall or short, a person's height increases their risk for a variety of diseases, according to a new study led by Sridharan Raghavan of the Rocky Mountain Regional VA Medical Center, U.S. publishing June 2nd in the ...

Diseases, Conditions, Syndromes

Scientists develop test that easily detects variants causing COVID-19

Rutgers scientists have developed a lab test that can quickly and easily identify which variant of the virus causing COVID-19 has infected a person, an advance expected to greatly assist health officials tracking the disease ...

Neuroscience

Enzyme prevents brain activity from getting out of control

Our bodies have the ability to modify the contacts between neurons. Among other things, this is how it prevents brain activity from getting out of control. Researchers from the University Hospital Bonn, together with a team ...

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DNA sequence

A DNA sequence or genetic sequence is a succession of letters representing the primary structure of a real or hypothetical DNA molecule or strand, with the capacity to carry information as described by the central dogma of molecular biology.

The possible letters are A, C, G, and T, representing the four nucleotide bases of a DNA strand — adenine, cytosine, guanine, thymine — covalently linked to a phosphodiester backbone. In the typical case, the sequences are printed abutting one another without gaps, as in the sequence AAAGTCTGAC, read left to right in the 5' to 3' direction. Short sequences of nucleotides are referred to as oligonucleotides and are used in a range of laboratory applications in molecular biology. With regard to biological function, a DNA sequence may be considered sense or antisense, and either coding or noncoding. DNA sequences can also contain "junk DNA."

Sequences can be derived from the biological raw material through a process called DNA sequencing.

In some special cases, letters besides A, T, C, and G are present in a sequence. These letters represent ambiguity. Of all the molecules sampled, there is more than one kind of nucleotide at that position. The rules of the International Union of Pure and Applied Chemistry (IUPAC) are as follows:

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