An international team of researchers led by Cleveland Clinic's Lerner Research Institute has performed for the first time a wide-scale characterization of missense variants from 1,330 disease-associated genes. Published in ...
Oct 27, 2020
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For decades, people diagnosed with familial hypercholesterolemia have been instructed to minimize their consumption of saturated fats to lower cholesterol and reduce their risks of heart disease. But a new study published ...
Jul 6, 2020
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Precision medicine has the potential to tailor treatments to a patient's unique genetic sequence. But achieving this precision—or developing new drugs—requires knowing which genes are involved in disease.
May 4, 2020
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Traditional cardiovascular risk factors often assessed in an annual physical, such as blood pressure, cholesterol levels, diabetes, and smoking status, are at least as valuable in predicting who will develop coronary heart ...
Feb 18, 2020
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Having genetically higher testosterone levels increases the risk of metabolic diseases such as type 2 diabetes in women, while reducing the risk in men. Higher testosterone levels also increase the risks of breast and endometrial ...
Feb 10, 2020
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Researchers at Harvard Medical School and the New York State Department of Health have discovered how a common plasticizer associated with human reproductive abnormalities likely does its damage at the molecular level.
Jan 9, 2020
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Treatments have been hard to pinpoint for a rare neurological disease called Charcot-Marie-Tooth (CMT), in part because so many variations of the condition exist. So far, mutations on more than 90 genes have been positively ...
Oct 1, 2019
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Yale researchers have discovered how metastasis, the spread of cancer cells throughout the body, is triggered on the molecular level, and have developed a tool with the potential to detect those triggers in patients with ...
Jun 26, 2019
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Researchers with the Atlanta Veterans Affairs Medical Center and Emory University have found a link between high LDL cholesterol levels and early-onset Alzheimer's disease. The results could help doctors understand how the ...
May 28, 2019
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(HealthDay)—A large, new study has uncovered 24 genetic variations that help separate the apple-shaped people from the pear-shaped ones.
Feb 18, 2019
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