Gene therapy to the inner retina prevented blindness in a mouse model of the neuro-degenerative disorder CLN3 Batten disease. Adeno-associated viral (AAV)-mediated expression of the human CLN3 gene led to significant survival ...
Aug 11, 2020
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Women with a genetic predisposition for breast cancer were 2.5 times more likely to develop a malignancy than women with the same genetic risk who underwent bariatric or weight-loss surgery, according to a new study presented ...
Nov 5, 2019
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Anti-VEGF therapies are commonly used to stabilize deteriorating vision in patients with wet age-related macular degeneration (wet AMD). Vascular endothelial growth factor, or VEGF, is a signaling molecule that helps maintain ...
Dec 5, 2016
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New research published in Diabetologia shows that people carrying a certain genetic variant relating to vitamin D metabolism are more likely to benefit from a high-protein weight loss diet than those without it. The research ...
Sep 29, 2015
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Alzheimer's disease is a degenerative disorder affecting between 50 percent and 70 percent of all dementia sufferers. As neurons are killed slowly yet progressively, sufferers experience memory loss and confusion, which worsens ...
Nov 22, 2013
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Distal renal tubular acidosis (dRTA) develops in response to the loss of acid secretion by α-intercalated cells in the kidney. The inability to remove acid from the body results in low blood potassium levels (hypokalemia), ...
Sep 24, 2013
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Tens of millions of Europeans suffer from a hearing impairment of some degree. They range from the one child in 1,000 who is born deaf, to the many whose hearing is declining as they grow older.
Sep 24, 2013
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At least half of all cases of deafness that develop from birth through infancy in developed countries have a genetic basis, as do many cases of later onset progressive hearing loss. To date, at least 1,000 mutations occurring ...
Jun 20, 2013
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Some 16 per cent of European adults suffer from hearing loss that is severe enough to adversely affect their daily life. Hearing loss impacts on one's ability to communicate - to hear, process sound, and respond - which can ...
Feb 27, 2013
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New findings from a landmark clinical trial show that although certain gene variants may predict whether a person is likely to develop age-related macular degeneration (AMD), a potentially blinding eye disease that afflicts ...
Feb 12, 2013
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