Genetics

Study questions value of genetic risk scores

What's known as the genome-wide polygenic score, or GPS, combines information from many thousands of genetic markers, each with only a minimal effect, to produce an overall assessment of disease risk based on an individual's ...

Neuroscience

Statins could protect against motor neurone disease

High cholesterol has been found to be a possible risk factor for the development of motor neurone disease (MND), according to a large study of genetic data led in the UK by Queen Mary University of London, in collaboration ...

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Genetic marker

A genetic marker is a gene or DNA sequence with a known location on a chromosome and associated with a particular gene or trait. It can be described as a variation, which may arise due to mutation or alteration in the genomic loci, that can be observed. A genetic marker may be a short DNA sequence, such as a sequence surrounding a single base-pair change (single nucleotide polymorphism, SNP), or a long one, like minisatellites.

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